Thursday November 23, 2006
Adenosine and Digoxin !

Adenosine is relatively a safe medicine in treatment of PSVT (paroxysmal supraventricular tachycardia) due to its short half life of 7-10 secs. It is quickly metabolise via cellular uptake by erythrocytes and vascular endothelial cells.

But some anecdotal reports show that if digoxin (or digoxin and verapmil in combination) is already on board, there are chances of culminating into fatal ventricular fibrillation. FDA advise use of adenosine with digoxin or digoxin and verapamil (in combination) with crash cart available at bedside.


Reference: click to get article
1. Adenocard IV - fda.gov